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Low Ovarian Reserve #24


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#51 Dustyblue

Posted 24 September 2014 - 12:49 PM

Thinking of you halby :)

I've been mulling over this low AMH / low ovarian reserve issue, and am starting to think my FS really overstated how dire my situation is/was. My AMH is 5.5 which she thought was disastrous. She briefly showed me a graph that (by age) put me so far down the chart I thought I must be almost menopausal. But just looking online, I've found several other graphs that say 5.5 at age 39 is in the mid-normal range. An AMH of 2 is still nowhere near beyond hope according to the reading I've now done. Are they generally so dire in their predictions or did I just see a particularly gloomy one lol.

Also since found many stories of women conceiving (ivf or otherwise) with an AMH below 1. So it's all just not as dire as I thought.

Just some general pondering :)

Hope everyone's doing well.

#52 halby

Posted 24 September 2014 - 01:28 PM

Dustyblue I think they are really hung up on low amh and I dont let it get me down. I was told before my last collection that I wasnt probably spending my money wisely but wanted another go and with an amh of 2 I came out with 14 eggs, 12 fertilised and 9 in the freezer at days graded 2. I think we have good months and bad months. Hang in there and dont listen or let it get you down too much.

#53 Dustyblue

Posted 25 September 2014 - 09:19 AM

Exactly halby. My FS said they'd be lucky to get 3 or 4 eggs from me, and then look at you! I think your attitude to the whole issue is fantastic and it's certainly made me more positive :)

#54 Gordo's Girl

Posted 01 October 2014 - 12:12 PM

Hi ladies

Hope you are all doing well.

Halby - how are you going?  What's the latest?

I'm having to delay things even further now, with all my results coming back saying I have Giardia, and 50% chance of coeliac as well (have the genes, but serology negative so far).  My Gastro Specialist has said that until I am absorbing any nutrients and can get my iron and Vit D levels back up, there's no point in IVF - which sucks.

So, at this stage we have to go back for another Gastroscope in two months, and if all looks good (I have villous atrophy), then will be good to go - otherwise I then have to try the whole gluten free diet and see if that makes a difference.

I'll just have to carrying on business as usual until I get a chance to kick this off again.  I just hope I'm pregnant before I hit 42!!!

Going to keep popping in to check up on you all though, and wishing you all lots and lots of babydust.

x GG

#55 halby

Posted 12 November 2014 - 09:32 PM

just a "bump" ladies, how is everyone and where is everyone????

#56 Gordo's Girl

Posted 13 November 2014 - 03:18 PM

Hi Halby, and all the other ladies

Very quiet in here isn't it?

How are you doing Halby?  I'm guessing you may be getting ready for another transfer.  How many frosties have you got left?  Hopefully one little magic one in there for you x

I'm just waiting for my next Gastroenterologist appointment, which is 1st December, and then I should be able to get back into it .... finally.  This is the longest ever round for me - started in June, and still have all the drugs in my fridge!

I know it's my very last ever attempt, and it makes me feel really sad that it's unlikely my DD will have a sibling, but I feel I need to do this one more time to really feel like I've made as much effort as possible.

Would love to hear how everyone is going.

x GG

#57 Primadonna girl

Posted 20 November 2014 - 02:59 PM

Hi girls!

This is my second round of IVF and with an amh of 1.1 I had my baby boy first try! No frosties but more than happy with the result. I have just had my amh retested before commencing ivf and I was really worried about how much it had dropped. 2 years after and my amh is 3.7! I am shocked and so happy yet confused how it has more than tripled! It is still low so i'm not getting overly excited, but it's still positive news!

Last time I did a long down reg cycle with 300 of Gonal F and retrieved 3 eggs, this time i'm doing an antagonist cycle with a higher dose of 450 Puregon and am hoping for more eggs. Anyone done both protocols and can tell me what differences to expect? I'm glad antagonist cycle is shorter as I suffered from headaches, bloating and general discomfort, although my husband only remembers "b**chiness" if you ask him! LOL!

Hope my story brings hope to some ladies worried about low amh levels and would love to hear all about your experiences!

#58 halby

Posted 26 November 2014 - 07:49 PM

Hey GG fingers crossed for your appointment on the 1st of December to get the all clear to move forward. I truly know how you feel. My DD has such a big desire for a sibling and asks for one on many occasions really pulls deep at my heart and all I can say is for her to keep wishing and you never know what will happen. Funnily enough on Sunday after my transfer I took her to the shop for cake and chino and that was when she said it again for the first time in ages. I definately told her to keep wishing that day. So yes I have just had another transfer and am now 3dp3dt of 2 very pretty 9 cell grade 2 embryos. They really look nice, but hey so have my other 50 odd that I have transfered over the years. But in saying that I am really relaxed and have a nice sense of calm about me so that has to be good. I really am coming to terms with what will be will be. I now have 3 left in the freezer but hoping not to have to use them. Keep me posted on how your appointment goes.

Primadonna welcome and good luck. I have always taken little stock in amh, I know for some it has been very reflective but for me it hasnt. My amh of 2 and I got 14 eggs last cycle with 9 embryos all grade 2 frozen on day 3. While I am still trying to get pregnant off those mebryos that is more an age factor than and amh for me. This was an antogonist cycle but my DD was a long down reg. I love the length of antogonist and I was on 450 gonal and my moods were fine. Good luck and fingers crossed for a few bfp's in this group. I hope I can get the ball rolling for us.

#59 causeway

Posted 29 November 2014 - 04:22 PM

Hi Ladies,
It’s a bit slow in here, isn’t it?
Halby – How you doing? BT must be early next week for you? I hope you get your Christmas Present!
GG – big day on Monday. I hope your specialist appointment goes well and that you can get back into your cycle! I,m pretty sure that there is a 3 year old birthday coming up at your house next week. Enjoy your day with your DD – I’m sure she will be spoilt.
Thought I’d pop in with an update.
I am currently CD13 on my final round of IVF. I am on 600iui Menopur with Syneral morning and night. So far, so good. I have two follicles which are growing at the appropriate rate. Oestrogen looks OK too. Was originally scheduled for EPU on Monday but have now been pushed to Wednesday due to follicles on the smaller side. Although on a different type of cycle, follicle size etc. is very reminiscent of my successful cycle with DD. Mood wise I’m doing OK. Am starting to feel bloated and very tired. I had a BT on Friday, results on Monday so if for some reason bloods aren’t so good, then we’ll trigger and do IUI. I told my FS on Friday that emotionally, I’m very removed from this process. Lets face facts, I’m 40 with an AMH of basically NIL. I’ve more chance of failing than succeeding. I already have a child and was extremely lucky to only take two cycles. I’ve decided that if it’s a BFN for me then I will do monitored cycles and IUI next year. We have plenty of semen in the freezer, DH works away so timing can be difficult. My FSH is fluctuating all over the place so with Day 3 bloods, we can hopefully predict a cycle with lower FSH and try to  take advantage of it. I am lucky now that I live 10 mins from my specialist. So, Wednesday is the day and then transfer will be Friday. BT will be Weds 17 December so hoping for an early Christmas present!
Will be stalking for updates.

#60 causeway

Posted 03 December 2014 - 11:20 AM

Hi - update from me.
EPU this morning and despite having two follicles we got 1 egg. Now the waiting game begins. Fertilisation results tomorrow and hopefully a transfer on Friday.
Hope all is well with you all xxx

#61 causeway

Posted 04 December 2014 - 10:02 AM

No fertilisation so it's all over. I'm sad. I'm blessed! I'm annoyed! I'll get over it! I feel old. I wish I had a job to go to!

#62 halby

Posted 04 December 2014 - 02:48 PM

Causeway, sh*t sh*t sh*t!!!
I am so sorry and here I am about to winge that I only have 3 embryos left to try give DD a sibling. Big huge hugs to you girl. I so understand how you are feeling. I went for beta this morning and just waiting for "The Call" but dh woke me early to poas and that is even what he said bless him but it was bfn. He really thought I was and to be honest had anyone asked me 5 days ago I would have said for sure I was pregnant as on Saturday I had such bad cramps that I would have said implantation guaranteed and even now I have this awful back ache that I hvae gotten when pregnant and sitting here starving. He wants me to hold onto some hope and I am just trying to tell myself maybe a late implanter like DD I dont think she would have shown up a bfp on a hpt today either as hcg at 16dpo with her was only 80, and today is 14dpo. DD just crushed me this morning as she told me she wants a little sister, I can tell you it was hard holding back the tears. For once I told her more than I normally do and said that mummy is always trying but I have a hard time having babies. She asked why was my tummy big then. "because I've put on wieght" I couldnt say that ivf over the past 5 years has cost me another 10 bloody kilos, and that I am bloated from the pesaries. I just want to scream "why if not for me then atleast for her"Oh well time to eat some comfort food while I await the call.
Work is overated causeway I cant get my head into it at all
Hi GG how did everything go at the appointment? Hi to everyone else I wish someone had some bloody good news....

#63 causeway

Posted 04 December 2014 - 04:55 PM

Thanks Halby - your post made me smile. I do hope you get a surprise but I think if we think with our heads and not our hearts we know the answer. I'm OK. DH and I've talked. At my last appointment with my lovely FS we discussed the what it's.... So moving forward we are going to monitor my FSH on day 3 and if we get a low result, we'll do injectables and IUI. DH works away so we've got more chance using frozen semen which is currently stickpiled. I've decided that I'm going to take a new tact in trying to find work and declare 2015 'all about me'. Once we get back from Christmas I'm going start looking after me, I'm going to declutter and start to sell off my baby stuff. I'll start with my maternity clothes and then the baby clothes. A very good friend is having a baby in March so hopefully I can pass things on to her. It might take me a few months to be ok with giving everything away but I'll get there. New chapter and all that.
Hi to everyone and I wish everyone all the best in their journeys. One thing I will add.... AMH is just an indicator. It is not a diagnosis. I conceived and delivered a healthy baby with an AMH of 2 at 37. At 38 my AMH was less than 1 and now I have rising FSH levels to contend with. I will check in with you all from time to time.

#64 nimble

Posted 19 January 2015 - 09:53 AM

Hi everyone - hope it's ok if I rejoin the group.  I was on here a while ago but under a different name, before I had DS.  Have changed name as I know quite a lot of EB members IRL now and just want to keep my journey under wraps for the moment.

My AMH is currently sitting on 2.8 and have just started my first IVF cycle.  At 39 years of age, and with my low AMH, I am quite pessimistic but I guess I hope that, perhaps, I might get lucky.  

Anyway, just wanted to say hi and hope you're all doing ok and that good news is just around the corner for you x

#65 Primadonna girl

Posted 22 January 2015 - 02:55 PM

Hi Nimble,

It sure is quiet in this forum! I wrote on here about a month ago and there hasn't been much activity. I am 35 with amh of 3.7 and have just gone through a failed ivf cycle in search of my second child. I did ivf 2 years ago with amh 1.1 and was extremely lucky to get DS on the first go. No frosties then, or this last cycle so i'm on to ivf#3.

It is really hard going through this knowing I only ever get 1 blastocyst to transfer and none to freeze as it is a lot of pressure for it to work. That's just how LOR works I suppose, not many eggs left and we just have to keep trying to get that 1 good one that will stick. I focus on eating healthy and taking supplements to increase egg quality as that's all I can do.

Do you have a timeframe for when you start? I will begin stims mid Feb and will be doing an antagonist cycle with 450 menopur, what about you? I've never used menopur before and am googling like crazy to see comments and experiences with it. I hope my FS is right about it increasing egg quality and getting more blasts, maybe just 1 to freeze...that's all I ask!

Hope all the other ladies on here are doing well and please share your feelings and thoughts with us, as we're all in the same boat!

#66 nimble

Posted 22 January 2015 - 04:38 PM

Hi Primadonna girl!

Sorry to hear your second cycle didn't work out, but hopefully the new protocol will yield great results.  It's tough isn't it?  I had an AMH of 3.8 at 35.  Now it's 2.8, 4 years later.  No idea how it will affect things.  Which supplements are you taking?  It's great you've increased your AMH so much!

I'm currently doing an antagonist cycle, on 300iu Gonal F.  Another BT and scan tomorrow to see whether EPU will go ahead on Monday.  My lining looks good and 6 follies have grown nicely (well, not sure what to compare them to) and they were hoping another couple will catch up so will find out tomorrow.  I guess the worry now is that none will fertilise or survive.  Time will tell.

#67 Primadonna girl

Posted 23 January 2015 - 10:50 AM

Hi Nimble,

According to my FS, AMH can vary and there's nothing you can do to influence it. He says that my amh increase just indicates that I have maintained the same level of fertility in these past 2 years which is lucky as I was worried it would decrease to a level where donor eggs would be my only option.

The supplements prescribed by my FS are androgen cream (3 weeks prior to stims, finishing on first day of menses), melatonin (until egg retrieval) and CoQ10 300mg (until egg retrieval). I also take Maca root and royal jelly which my FS has said are fine to take. Hopefully it will all make a difference.

It really is a hard process emotionally, every step has the possibility to surprise you for good, or for bad. My first ivf U had 7 follicles and only 3 eggs were retrieved. I was devastated as I knew I still had to go through fertilisation and the 5 days of embryo development where lots can go wrong. In the end they all fertilised and only 1 made it to day 3 when we transferred, but that 1 is my son! So as my FS says, it's not about quantity but quality, what we need is just 1 good one!

This second cycle everything appeared to be going better, I had 8 eggs retrieved, 5 fertilised and 3 made it to day 5, we transferred 1 and ended up with none to freeze and a bfn. So don't pay too much attention to numbers as they can be deceiving! 6 follicles is good for LOR and let's just hope that there are some good ones in there!

Good luck with your BT and scan today, hope all is ready for Monday!

#68 Primadonna girl

Posted 31 January 2015 - 01:46 PM

Hey Nimble,

Just wondering how you went this week, hope you're ok.

#69 nimble

Posted 01 February 2015 - 09:28 AM

Hi Primadonna, so sorry, I thought I had replied to your post earlier!  That's great that the first cycle resulted in DS but so sorry about the second one.

What meds were you on for those two cycles?  I'm still very new to all the different drugs, and haven't had much time to research them all.  I was on gonal f (300iu).  Hopefully the new protocol will yield some good results for you in Feb/Mar!

I'd forgotten about royal jelly, melatonin etc.  I need to go back on DHEA and all of those if this one doesn't work.  Booked in with a TCM next week to get my body a bit more prepared as feel like I wasn't as prepared as I could be for this first cycle.

This week went ok; had 5 eggs retrieved, but only 1 made it to blastocyst and was transferred yesterday so am officially in the 2ww.  Not enjoying the progesterone pessaries! We are treating it as a bit of a trial run, though, and neither me nor DH are expecting much.

Edited by nimble, 01 February 2015 - 09:28 AM.


#70 Primadonna girl

Posted 02 February 2015 - 05:03 PM

Hi Nimble,

It's great that you had a blast transferred! The first cycle really is s trial run to get to know your body and how you react to the stims. I know what you mean about not being fully prepared for the cycle, I felt that way about cycle 2 aswell. For the next cycle I am doing everything I can to try and make it the last one!

The pessaries are aweful! Just as you finish the injections, you start the pessaries! Not looking forward to that part again, come to think of it i'm not looking forward to any of it! It's the price we must pay unfortunately but well worth it, if it works out of course!

The first cycle I was on 300ui Gonal F on long down regulation which got 3 eggs, a 3 day transfer and bfp. The second cycle I was on 450ui Puregon antagonist which got 8 eggs (5 mature), 3 blasts, 1 transferred which was bfn and no frosties. The third cycle i'll be on 450ui Menopur antagonist to try and increase the quality of the eggs rather than the quantity.

It's all so personal as we all react differently but my bfp was after long down reg and this new FS says that it suppresses your ovaries too much if you have LOR, so antagonist is better. I have to trust him but it's hard seeing the outcomes.

You must be going crazy reading into your symptoms at the moment, I know I did! You get the same symptoms for pessary use, bfp and period coming so I think it's our hope that pushes us to think it's a bfp! The only difference I found between the symptoms of bfp and bfn was that I had really painful and intense cramping especially while sleeping when I was pregnant, whereas they were mild when I wasn't. But then again each pregnancy is different and that's what I kept telling myself when I was convincing myself that I was pregnant when I wasn't!

Hope your 2ww goes quickly and fingers crossed it all works out for you!

#71 nimble

Posted 04 February 2015 - 09:38 AM

Thanks Primadonna girl! I'm trying to not think too much about things, but did have some EWCM this morning which is unusual for me in the LP. But it's prob just something to do with the progesterone. I'll know one way or another in a weeks time.

With my first BFP, my only early symptoms were very sore nipples (showering was unbearable) and a bit tired. However, was on holiday at the time and jet lagged so would have been tired anyway. Otherwise I never really got anything until later on.

How are you going? What are you doing to prep for the next cycle?

#72 Guest_MummaKay_*

Posted 04 February 2015 - 02:45 PM

Hi there,

Just wanted to introduce myself. Hello!

My background:
After having my son 4.5 years ago, I underwent fertility testing to see what our chances were of a second, we wanted to work out how long a gap we should leave. I am a Fragile X carrier, so knew early menopause was a risk, however I was still floored to hear my AMH was undectable... The fertility specialist said it was an equivelant result to a 48 year old woman (I was 30 at the time). We were told not to wait, but that our chances of conception were less than 5%. I got pregnant that very cycle and now have two children. I've also suffered a miscarriage in the last year. This doesn't seem to add up/be possible from what I understand.

We're headed to Genea to try our luck for number 3. We have not been trying naturally... but I know AMH is a good predictor of success with IVF, has anyone had success with such a terrible number? I'm scared.

Thanks,

BB.

Edited by MummaKay, 04 February 2015 - 02:46 PM.


#73 Primadonna girl

Posted 06 February 2015 - 02:12 PM

Hi girls!

Nimble- did you use ART for your first pregnancy? I had such strong cramps due to high progesterone levels I think. I stopped the pessaries straight away after the positive beta and the cramping slowly went away.

I only have 1 week left before AF comes and I start IVF 3. I have been on all the supplements I told you about and trying to eat more healthily. I do eat a very balanced, organic diet anyway but I have a terrible sweet tooth and chocolate is my obsession! No caffeine, less chocolate and sweets, no soft drinks etc. Other than that there isn't much else I can do to increase egg quality, I wish there was a proven formula!

Mumma Kay- I tested amh of 1.1 two years ago when I did IVF 1 which resulted in my DS. I did a cycle in Nov last year and my FS said that if it was significantly lower, he would not recommend IVF with my own eggs. Luckily it came back at 3.7 and we are trying again as IVF 2 was BFN. I'm sure that i've read stories of women falling pregnant naturally with undetectable levels and they bring us all great hope. Nothing is predictable and every woman is different and reacts differently to the stims too. I hope you are one of the lucky ones we'll all read about!

#74 Shaynavyre

Posted 05 March 2015 - 04:56 PM

I just wanted to add in that I am also a strangely improving AMH too. At 27 years when I was first tested, it was 7.2 which the FS said was very dire indeed. (The AMH of a 41yo were her exact words.)

Fast forward to august last year,  (I'm 30)and it had almost doubled (I still think there may have been a lab error but FS says no point in testing it again).


I was briefly on the bcp post miscarriage to get my cycle back near to when I had the initial Amh done and apparently that can influence it - but not by as much as seen in me.

#75 ~Mintie~

Posted 28 April 2015 - 12:20 PM

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